Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741970 | 0.91 | MAOB (0.57) | MAOBMAOARAB9ANPC1L3MBTL1 | |
| SCHEMBL6201009 | 0.90 | MAOB (0.59) | MAOBMAOARAB9ANPC1L3MBTL1 | |
| SCHEMBL1066576 | 0.88 | TSHR (0.67) | RAB9ANPC1L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL1164267 | 0.86 | L3MBTL1 (0.68) | MAOBMAOARAB9ANPC1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1409425 | 0.86 | TSHR (0.64) | MAOBMAOARAB9ANPC1L3MBTL1 | |
| SCHEMBL14378833 | 0.86 | TSHR (0.71) | MAOBMAOARAB9ANPC1L3MBTL1 | |
| Water SCHEMBL28780406 | 0.86 | TSHR (0.64) | RAB9ANPC1L3MBTL1TSHRTDP1 | |
| SCHEMBL28716976 | 0.82 | TSHR (0.54) | L3MBTL1TSHRTDP1TAAR1IDO1 | |
| SCHEMBL6744772 | 0.82 | ESR1 (0.54) | MAOBL3MBTL1TSHRTDP1IDO1 | |
| SCHEMBL1837574 | 0.82 | ESR1 (0.54) | MAOBL3MBTL1TSHRTDP1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011667-A4 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO INC (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-1011667-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-06-28 | — | — | EP | disclosed |
| US-5985901-A | TREATMENT OF A VARIETY OF SEX-HORMONE RELATED AND OTHER CONDITIONS IN BOTH MEN AND WOMEN | MERCK & CO., INC. (US) | 1999-11-16 | — | — | US | disclosed |
| WO-1998055119-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1998-12-10 | — | — | WO | disclosed |