Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | FURIN | P09958 | 4/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922670 | 1.00 | CTSD (0.41) | CTSDBACE1FURINDPP8DPP9 | |
| SCHEMBL29366972 | 0.93 | GSR (0.41) | FURINDPP8DPP9DPP7GSR | |
| SCHEMBL29404549 | 0.91 | ACE (0.46) | FURINDPP8DPP9DPP7GSR | |
| SCHEMBL28220840 | 0.91 | GSR (0.47) | CTSDBACE1FURINDPP8DPP9 | |
| SCHEMBL28220832 | 0.91 | GSR (0.47) | CTSDBACE1FURINDPP8DPP9 | |
| SCHEMBL31472967 | 0.90 | DPP8 (0.39) | FURINDPP8DPP9DPP7GSR | |
| SCHEMBL29527624 | 0.90 | ACE (0.43) | FURINDPP8DPP9DPP7GSR | |
| SCHEMBL31609083 | 0.90 | BACE1 (0.42) | CTSDBACE1FURINDPP8DPP9 | |
| SCHEMBL30361652 | 0.88 | BACE1 (0.45) | CTSDBACE1FURIN | |
| SCHEMBL676551 | 0.88 | BACE1 (0.45) | CTSDBACE1FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1225171-A | Direct electrochemistry of enzymes | BRITISH GAS PLC (GB) | 1999-08-04 | — | — | CN | claimed |
| EP-0897537-A1 | DIRECT ELECTROCHEMISTRY OF ENZYMES | BG plc (GB) | 1999-02-24 | — | — | EP | claimed |
| WO-1997043632-A1 | DIRECT ELECTROCHEMISTRY OF ENZYMES | BG PLC (GB) | 1997-11-20 | — | — | WO | claimed |
| US-6231746-B1 | MONOOXYGENASE | BG PLC (GB) | 2001-05-15 | — | — | US | disclosed |
| CN-1225171-A | Direct electrochemistry of enzymes | BRITISH GAS PLC (GB) | 1999-08-04 | — | — | CN | disclosed |
| EP-0897537-A1 | DIRECT ELECTROCHEMISTRY OF ENZYMES | BG plc (GB) | 1999-02-24 | — | — | EP | disclosed |
| WO-1997043632-A1 | DIRECT ELECTROCHEMISTRY OF ENZYMES | BG PLC (GB) | 1997-11-20 | — | — | WO | disclosed |
| WO-1990006323-A2 | CHIMERIC PROTEINS INCORPORATING A METAL BINDING PROTEIN | CENTOCOR, INC. (US) | 1990-06-14 | — | — | WO | disclosed |