Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29169496 | 0.86 | PPARD (0.50) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL13934351 | 0.82 | PPARD (0.50) | PPARDTSHRTP53CA12CA1 | |
| SCHEMBL2991834 | 0.80 | PPARD (0.58) | PPARDTSHRTDP1TP53HTT | |
| SCHEMBL1276434 | 0.80 | PPARD (0.58) | PPARDTSHRTDP1TP53CA12 | |
| SCHEMBL14549069 | 0.79 | PPARD (0.57) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL13921035 | 0.79 | PPARD (0.47) | PPARDTSHRTDP1TP53CA12 | |
| SCHEMBL28021210 | 0.78 | PPARD (0.56) | PPARDTSHRTDP1TP53CA12 | |
| SCHEMBL7425644 | 0.78 | PPARD (0.56) | PPARDTSHRTDP1TP53HTT | |
| SCHEMBL5839773 | 0.78 | PPARD (0.56) | PPARDTSHRTDP1TP53HTT | |
| SCHEMBL712616 | 0.77 | TSHR (0.50) | PPARDTSHRTDP1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095050-A1 | PHOSPHOROUS ORGANIC COMPOUNDS AND THEIR USE | Jomaa, Hassan (DE) | 2001-05-02 | — | — | EP | disclosed |
| WO-2000004031-A1 | PHOSPHOROUS ORGANIC COMPOUNDS AND THEIR USE | JOMAA HASSAN (DE) | 2000-01-27 | — | — | WO | disclosed |