SCHEMBL7922677

SCHEMBL7922677

C=CCOC(=O)CC(O)(CC(=O)OCC=C)C(=O)OCC=C.O[Si](O)(O)O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.36
NPSR1 Q6W5P4 1/20 0.33
CYP3A4 P08684 1/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.32
CACNA1B Q00975 1/20 0.32
APBA1 Q02410 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173249 0.94 TSHR (0.42) TSHRTDP1NPSR1CYP3A4PKM
Lithium SCHEMBL30776951 0.93 TSHR (0.41) TSHRTDP1NPSR1CYP3A4PKM
SCHEMBL10446643 0.88 TSHR (0.38) TSHRTDP1NPSR1CYP3A4PKM
Acetic Acid SCHEMBL9743919 0.88 TSHR (0.41) TSHRTDP1NPSR1CYP3A4PKM
SCHEMBL2576138 0.88 ALDH1A1 (0.38) TSHRTDP1NPSR1CYP3A4PKM
SCHEMBL1071336 0.85 TSHR (0.39) TSHRTDP1NPSR1CYP3A4PKM
SCHEMBL907822 0.83 TDP1 (0.36) TSHRTDP1NPSR1CYP3A4PKM
Ethylene Glycol SCHEMBL1071330 0.83 TSHR (0.35) TSHRTDP1NPSR1CYP3A4PKM
SCHEMBL1538370 0.83 TSHR (0.40) TSHRTDP1NPSR1CYP3A4PKM
SCHEMBL10446645 0.82 TSHR (0.39) TSHRTDP1NPSR1CYP3A4PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1105429-A1 ANTIMICROBIAL POLYMER LATEXES DERIVED FROM UNSATURATED QUATERNARY AMMONIUM COMPOUNDS AND ANTIMICROBIAL COATINGS, SEALANTS, ADHESIVES AND ELASTOMERS PRODUCED FROM SUCH LATEXES STEPAN COMPANY (US) 2001-06-13 EP disclosed
WO-2000006612-A1 ANTIMICROBIAL POLYMER LATEXES DERIVED FROM UNSATURATED QUATERNARY AMMONIUM COMPOUNDS AND ANTIMICROBIAL COATINGS, SEALANTS, ADHESIVES AND ELASTOMERS PRODUCED FROM SUCH LATEXES STEPAN COMPANY (US) 2000-02-10 WO disclosed