Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3302100 | 1.00 | BACE1 (0.55) | BACE1KCNH2CTSDCTSB | |
| SCHEMBL2341633 | 1.00 | BACE1 (0.55) | BACE1KCNH2CTSDCTSB | |
| SCHEMBL2620310 | 0.85 | BACE1 (0.47) | BACE1CTSDCTSB | |
| SCHEMBL2927948 | 0.85 | BACE1 (0.47) | BACE1CTSDCTSB | |
| SCHEMBL7915547 | 0.83 | BACE1 (0.64) | BACE1KCNH2CTSDCTSB | |
| SCHEMBL3295791 | 0.83 | BACE1 (0.64) | BACE1KCNH2CTSDCTSB | |
| SCHEMBL3295793 | 0.83 | BACE1 (0.64) | BACE1KCNH2CTSDCTSB | |
| SCHEMBL7927114 | 0.77 | BACE1 (0.59) | BACE1KCNH2 | |
| SCHEMBL3299449 | 0.77 | BACE1 (0.59) | BACE1KCNH2 | |
| SCHEMBL9913157 | 0.77 | BACE1 (0.59) | BACE1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038686-A1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | エーザイ・アール・アンド・ディー・マネジメント株式会社 (JP) | 2010-04-08 | — | — | WO | disclosed |