Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3447191 | 0.86 | MEN1 (0.43) | TDP1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL11766103 | 0.85 | MEN1 (0.45) | TDP1MEN1KMT2ACYP3A4LMNA | |
| SCHEMBL11766109 | 0.85 | MEN1 (0.45) | TDP1MEN1KMT2ACYP3A4LMNA | |
| SCHEMBL7136449 | 0.80 | CYP3A4 (0.41) | TDP1POLBHTTAPEX1MEN1 | |
| SCHEMBL28678088 | 0.78 | MEN1 (0.40) | TDP1MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL27939045 | 0.78 | MEN1 (0.40) | TDP1HTTMEN1KMT2ACYP3A4 | |
| SCHEMBL2120464 | 0.78 | TSHR (0.39) | TDP1POLBHTTAPEX1KDM4E | |
| SCHEMBL5864403 | 0.77 | TDP1 (0.47) | TDP1POLBHTTAPEX1KDM4E | |
| SCHEMBL27939088 | 0.76 | MEN1 (0.39) | TDP1MEN1KMT2ACYP3A4GLA | |
| SCHEMBL2246299 | 0.76 | MEN1 (0.39) | TDP1KDM4EMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6224004-B1 | Mill provided with partition within milling chamber | MINOLTA CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |