Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.43 |
| ▸ | MAOB | P27338 | 12/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1391325 | 0.89 | MAOA (0.43) | MAOAMAOBCA9CA12CA1 | |
| SCHEMBL1391350 | 0.87 | MAOA (0.51) | MAOAMAOBCA9CA12CA1 | |
| SCHEMBL2318663 | 0.86 | NPC1 (0.49) | MAOAMAOBNPC1ACACBACACA | |
| SCHEMBL1392027 | 0.85 | MAOA (0.41) | MAOAMAOBCA9CA12CA1 | |
| SCHEMBL1390937 | 0.84 | MAOB (0.51) | MAOAMAOBNPC1SLC16A3ACACB | |
| SCHEMBL12433342 | 0.83 | MAOA (0.53) | MAOAMAOBCA12CA1CA2 | |
| SCHEMBL1390787 | 0.81 | MAOA (0.51) | MAOAMAOBCA12CA1CA2 | |
| SCHEMBL1390722 | 0.81 | MAOA (0.64) | MAOAMAOBCA9CA12CA1 | |
| SCHEMBL1390584 | 0.80 | ACACB (0.50) | MAOAACACBACACA | |
| SCHEMBL1391226 | 0.80 | NPC1 (0.49) | NPC1ACACBACACARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050445-A1 | BICYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |