Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5513548 | 0.83 | PLAU (0.44) | PLAUALDH1A1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL2445157 | 0.78 | ALDH1A1 (0.57) | PLAUALDH1A1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL20356018 | 0.77 | CYP1A2 (0.46) | ALDH1A1TYMSSLC6A2SLC6A4KCNH2 | |
| SCHEMBL5508151 | 0.77 | PLAU (0.38) | PLAUALDH1A1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL8121539 | 0.76 | ALDH1A1 (0.55) | PLAUALDH1A1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL5514092 | 0.76 | ALDH1A1 (0.44) | PLAUALDH1A1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL6308995 | 0.76 | CYP2A6 (0.44) | TYMSPOLBESR1ESR2 | |
| SCHEMBL24664098 | 0.75 | PLAU (0.38) | PLAUALDH1A1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL30988504 | 0.75 | PLAU (0.38) | PLAUALDH1A1CYP3A4HSD17B10ALOX15 | |
| SCHEMBL30988506 | 0.75 | PLAU (0.38) | PLAUALDH1A1CYP3A4HSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001019649-A | NEW LIQUID CRYSTAL COMPOUND, 6-FLUORO-NAPHTHALENE DEIVATIVE AND LIQUID CRYSTAL COMPOSITION CONTAINING THE SAME | DAINIPPON INK & CHEM INC | 2001-01-23 | — | — | JP | disclosed |