Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 4/20 | 0.53 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.51 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685760 | 0.99 | AHCY (0.54) | AHCYEHMT1EHMT2TSHRHSP90B1 | |
| SCHEMBL6692383 | 0.89 | AHCY (0.54) | AHCYEHMT1ADORA3ADORA2AADORA2B | |
| SCHEMBL19066616 | 0.87 | AHCY (0.58) | AHCYTSHRHSP90B1MAPK1ADORA3 | |
| SCHEMBL6697082 | 0.87 | AHCY (0.52) | AHCYEHMT1ADORA3ADORA2AADORA2B | |
| SCHEMBL6695446 | 0.87 | AHCY (0.53) | AHCYEHMT1EHMT2HSP90B1ADORA3 | |
| SCHEMBL6698657 | 0.85 | AHCY (0.55) | AHCYTSHRHSP90B1MAPK1ADORA3 | |
| SCHEMBL177772 | 0.82 | AHCY (0.61) | AHCYTSHRHSP90B1MAPK1ADORA3 | |
| SCHEMBL28901883 | 0.82 | AHCY (0.61) | AHCYTSHRHSP90B1MAPK1ADORA3 | |
| SCHEMBL29877256 | 0.82 | AHCY (0.61) | AHCYTSHRHSP90B1MAPK1ADORA3 | |
| SCHEMBL1093486 | 0.81 | EHMT1 (0.56) | AHCYEHMT1EHMT2MAPK1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6211165-B1 | GENE EXPRESSION; BINARY CONJUGATES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-04-03 | — | — | US | disclosed |