Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.62 |
| ▸ | CNR1 | P21554 | 5/20 | 0.57 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.50 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467928 | 0.90 | HDAC1 (0.60) | CNR2CNR1 | |
| SCHEMBL7920596 | 0.89 | CNR2 (0.61) | CNR2CNR1 | |
| SCHEMBL3467225 | 0.85 | HDAC1 (0.57) | CNR2CNR1 | |
| SCHEMBL3467213 | 0.82 | HDAC1 (0.67) | CNR2CNR1 | |
| SCHEMBL3467463 | 0.82 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL7917237 | 0.82 | HDAC1 (0.56) | CNR2CNR1 | |
| SCHEMBL3467892 | 0.80 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL3467087 | 0.80 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL3468139 | 0.80 | CNR2 (0.58) | CNR2CNR1 | |
| SCHEMBL18229445 | 0.80 | LMNA (0.71) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073078-A2 | HETEROCYCLIC COMPOUNDS AS HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LTD. (IN) | 2010-07-01 | — | — | WO | disclosed |