Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL2183961 | 1.00 | — | — | |
| Nitric Acid SCHEMBL7924915 | 1.00 | CA5A (0.42) | CA5ACA5BALDH1A1TDP1SMN1; SMN2 | |
| Nitric Acid SCHEMBL2733753 | 0.86 | CA5A (0.50) | CA5ACA5BALDH1A1TDP1ALOX15 | |
| Nitric Acid SCHEMBL22117372 | 0.86 | CA5A (0.50) | CA5ACA5BALDH1A1TDP1ALOX15 | |
| SCHEMBL43613 | 0.80 | — | — | |
| Nitric Acid SCHEMBL29142703 | 0.79 | — | — | |
| Diethanolamine SCHEMBL8754524 | 0.78 | CA5A (0.47) | CA5ACA5BALDH1A1TDP1 | |
| Diethanolamine SCHEMBL1585206 | 0.78 | CA5A (0.47) | CA5ACA5BALDH1A1TDP1 | |
| Diethanolamine SCHEMBL9901053 | 0.78 | CA5A (0.47) | CA5ACA5BALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL9104096 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8636860-B2 | Ionic liquid monopropellant gas generator | STREAMLINE AUTOMATION, LLC (US) | 2014-01-28 | — | — | US | claimed |
| US-20120138859-A1 | Ionic Liquid Monopropellant Gas Generator | THE UNIVERSITY OF ALABAMA (US) | 2012-06-07 | — | — | US | claimed |
| US-6218577-B1 | SALT FORMATION BY REACTION 2-HYDROXYETHYLHYDRAZINE WITH NITRIC ACID, PERCHLORIC ACID, TRINITROMETHANE OR DINITROAMINE; EXPLOSIVES, PROPELLANTS; LESS TOXIC | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2001-04-17 | — | — | US | disclosed |