SCHEMBL7925004

SCHEMBL7925004

O=C[Fe](C=O)CC#CC1=CCCCC1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.38
CYP1A2 P05177 2/20 0.36
GRM5 P41594 2/20 0.36
CTSK P43235 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
ATM Q13315 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7925007 0.78 FFAR1 (0.39) FFAR1CYP1A2GRM5CTSKNPC1
SCHEMBL551632 0.71 FFAR1 (0.44) FFAR1CYP1A2GRM5CTSKNPC1
SCHEMBL29080299 0.70 CYP1A2 (0.39) FFAR1CYP1A2GRM5
SCHEMBL4212451 0.65
SCHEMBL4854449 0.64
SCHEMBL5774580 0.64
SCHEMBL4222484 0.64
SCHEMBL11746719 0.64
SCHEMBL11744141 0.64
SCHEMBL2232295 0.63 FFAR1 (0.55) FFAR1CYP1A2GRM5NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242478-B1 ANTICARCINOGENIC AGENTS; REPLICATION INHIBITORS OF HUMAN LYMPHADENOPATHY ASSOCIATED VIRUS(HIV) WAKE FOREST UNIVERSITY 2001-06-05 US disclosed