Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7925004 | 0.78 | FFAR1 (0.38) | FFAR1CYP1A2GRM5CTSKNPC1 | |
| SCHEMBL551632 | 0.72 | FFAR1 (0.44) | FFAR1CYP1A2GRM5CTSKNPC1 | |
| SCHEMBL262534 | 0.68 | — | — | |
| SCHEMBL29080299 | 0.68 | CYP1A2 (0.39) | FFAR1CYP1A2GRM5 | |
| SCHEMBL2193339 | 0.66 | — | — | |
| SCHEMBL2194006 | 0.66 | CYP1A2 (0.39) | FFAR1CYP1A2GRM5CTSKNPC1 | |
| SCHEMBL19280743 | 0.66 | CYP1A2 (0.39) | FFAR1CYP1A2GRM5CTSKNPC1 | |
| SCHEMBL4212451 | 0.66 | — | — | |
| SCHEMBL4222484 | 0.65 | — | — | |
| SCHEMBL4854449 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242478-B1 | ANTICARCINOGENIC AGENTS; REPLICATION INHIBITORS OF HUMAN LYMPHADENOPATHY ASSOCIATED VIRUS(HIV) | WAKE FOREST UNIVERSITY | 2001-06-05 | — | — | US | disclosed |