Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300585 | 1.00 | BACE1 (0.45) | BACE1BACE2 | |
| SCHEMBL2619829 | 0.87 | BACE1 (0.35) | BACE1BACE2 | |
| SCHEMBL12690003 | 0.87 | BACE1 (0.35) | BACE1BACE2 | |
| SCHEMBL12690280 | 0.87 | BACE1 (0.35) | BACE1BACE2 | |
| SCHEMBL13177584 | 0.87 | BACE1 (0.35) | BACE1BACE2 | |
| SCHEMBL14716826 | 0.84 | BACE1 (0.47) | BACE1BACE2 | |
| SCHEMBL14746903 | 0.84 | BACE1 (0.47) | BACE1BACE2 | |
| SCHEMBL7927023 | 0.82 | BACE1 (0.33) | BACE1 | |
| SCHEMBL3302614 | 0.82 | BACE1 (0.43) | BACE1BACE2 | |
| SCHEMBL9913098 | 0.80 | BACE1 (0.51) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038686-A1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | エーザイ・アール・アンド・ディー・マネジメント株式会社 (JP) | 2010-04-08 | — | — | WO | disclosed |