Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13177584 | 1.00 | BACE1 (0.35) | BACE1BACE2 | |
| SCHEMBL12690003 | 1.00 | BACE1 (0.35) | BACE1BACE2 | |
| SCHEMBL2619829 | 1.00 | BACE1 (0.35) | BACE1BACE2 | |
| SCHEMBL18517671 | 0.88 | HDAC4 (0.32) | — | |
| SCHEMBL18498598 | 0.88 | HDAC4 (0.32) | — | |
| SCHEMBL7925283 | 0.87 | BACE1 (0.45) | BACE1BACE2 | |
| SCHEMBL3300585 | 0.87 | BACE1 (0.45) | BACE1BACE2 | |
| SCHEMBL2619824 | 0.85 | HDAC4 (0.33) | BACE1 | |
| SCHEMBL8039235 | 0.85 | HDAC4 (0.33) | BACE1 | |
| SCHEMBL16418313 | 0.85 | HDAC4 (0.33) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245155-A1 | FUSED HETEROCYCLIC COMPOUND HAVING AMINO GROUP | SHIONOGI & CO., LTD. (JP) | 2012-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245155-A1 | FUSED HETEROCYCLIC COMPOUND HAVING AMINO GROUP | APP, IAPP, BACE1 | BACE1 3/4885BACE2 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.