Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 15/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6155755 | 0.78 | SIGMAR1 (0.61) | SIGMAR1EPHX2EPHX1ARKCNH2 | |
| SCHEMBL17710474 | 0.73 | SIGMAR1 (0.54) | SIGMAR1EPHX2EPHX1ARKCNH2 | |
| SCHEMBL6724127 | 0.72 | SIGMAR1 (0.52) | SIGMAR1EPHX2EPHX1 | |
| SCHEMBL6156054 | 0.72 | SIGMAR1 (1.00) | SIGMAR1EPHX2EPHX1ARKCNH2 | |
| Hydrochloric Acid SCHEMBL6158171 | 0.71 | SIGMAR1 (1.00) | SIGMAR1EPHX2EPHX1ARKCNH2 | |
| SCHEMBL2740883 | 0.68 | SIGMAR1 (0.66) | SIGMAR1EPHX2EPHX1GRIN2DGRIN3B | |
| SCHEMBL6154324 | 0.66 | EPHX2 (0.44) | SIGMAR1EPHX2 | |
| SCHEMBL6155548 | 0.66 | SIGMAR1 (0.62) | SIGMAR1EPHX2EPHX1ARKCNH2 | |
| SCHEMBL6155761 | 0.65 | SIGMAR1 (0.67) | SIGMAR1EPHX2EPHX1ARKCNH2 | |
| SCHEMBL3073550 | 0.65 | SIGMAR1 (1.00) | SIGMAR1EPHX2EPHX1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242198-B1 | ADMINISTERING GUANIDINE COMPOUND | CAMBRIDGE NEUROSCIENCE, INC. | 2001-06-05 | — | — | US | disclosed |