Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 19/20 | 0.79 |
| ▸ | PIK3CA | P42336 | 19/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2281969 | 0.89 | MTOR (1.00) | MTORPIK3CA | |
| SCHEMBL7922488 | 0.88 | MTOR (0.78) | MTORPIK3CA | |
| SCHEMBL7920281 | 0.85 | MTOR (0.79) | MTORPIK3CA | |
| SCHEMBL7923875 | 0.84 | PIK3CA (0.79) | MTORPIK3CA | |
| SCHEMBL7924993 | 0.84 | PIK3CA (0.59) | MTORPIK3CA | |
| SCHEMBL7913788 | 0.83 | MTOR (0.81) | MTORPIK3CA | |
| SCHEMBL7924523 | 0.80 | MTOR (0.81) | MTORPIK3CA | |
| SCHEMBL31439358 | 0.78 | PIK3CA (0.82) | MTORPIK3CA | |
| SCHEMBL2283474 | 0.76 | PIK3CA (1.00) | MTORPIK3CA | |
| SCHEMBL31439374 | 0.75 | MTOR (0.71) | MTORPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010038165-A1 | IMIDAZO[1,5]NAPHTHYRIDINE COMPOUNDS, THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2010-04-08 | — | — | WO | disclosed |