SCHEMBL7925562

SCHEMBL7925562

C=[Ti](OC(=O)c1cccc2ccccc12)(OC(=O)c1cccc2ccccc12)(C1=CC=CC1)C1C=Cc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
HRH3 Q9Y5N1 1/20 0.31
CDC25B P30305 1/20 0.31
MTNR1A P48039 1/20 0.31
MTNR1B P49286 1/20 0.31
MEN1 O00255 3/20 0.31
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
KCNH2 Q12809 1/20 0.31
PLK1 P53350 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7925654 0.86 KMT2A (0.32) KMT2APOLBGAAHRH3CDC25B
SCHEMBL7930743 0.84 TSHR (0.30) KMT2AMEN1
SCHEMBL7919260 0.83 KMT2A (0.37) KMT2APOLBGAAHRH3CDC25B
SCHEMBL7927659 0.82
SCHEMBL7919605 0.81 LMNA (0.31) ALDH1A1LMNA
SCHEMBL7919261 0.81 RET (0.31)
SCHEMBL7919299 0.80
SCHEMBL7927285 0.80 KMT2A (0.42) KMT2APOLBGAACDC25BMEN1
SCHEMBL7928318 0.80
SCHEMBL7927797 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed