SCHEMBL7925643

SCHEMBL7925643

C[Ti](C)(=[SiH2])(OC(=O)c1ccccc1)(OC(=O)c1ccccc1)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TSHR P16473 5/20 0.37
ATM Q13315 1/20 0.36
LMNA P02545 3/20 0.35
F2 P00734 1/20 0.35
ALDH1A1 P00352 2/20 0.33
MAPK1 P28482 2/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
HSD17B10 Q99714 1/20 0.33
P2RY2 P41231 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
P2RX4 Q99571 1/20 0.32
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7925897 0.90 RAB9A (0.34) MEN1KMT2ATSHRATMLMNA
SCHEMBL7930986 0.85 POLB (0.35) MEN1KMT2AATM
SCHEMBL7925603 0.81 RET (0.35) MEN1KMT2ALMNASMN1; SMN2
SCHEMBL7928114 0.81 MEN1 (0.30) MEN1KMT2A
SCHEMBL7930322 0.81 ELANE (0.31) MEN1KMT2ALMNANPSR1
SCHEMBL7930279 0.81 KCNN4 (0.41) MEN1KMT2AATM
SCHEMBL7925446 0.80 KMT2A (0.38) MEN1KMT2ALMNAALDH1A1MAPK1
SCHEMBL7925125 0.80 ATM (0.31) ATM
SCHEMBL7930543 0.80 ELANE (0.31)
SCHEMBL7930345 0.79 MEN1 (0.32) MEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed