Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771609 | 0.90 | SMO (0.47) | MTTP | |
| SCHEMBL7926795 | 0.90 | MTTP (0.52) | MTTP | |
| SCHEMBL6053015 | 0.89 | MTTP (0.52) | MTTP | |
| SCHEMBL6889715 | 0.88 | MTTP (0.66) | MTTP | |
| SCHEMBL6052958 | 0.88 | MTTP (0.49) | MTTP | |
| SCHEMBL6053025 | 0.86 | MTTP (0.49) | MTTP | |
| SCHEMBL6770179 | 0.86 | APOB (0.54) | MTTP | |
| SCHEMBL6890386 | 0.85 | MTTP (0.65) | MTTP | |
| SCHEMBL6052880 | 0.85 | APOB (0.55) | MTTP | |
| SCHEMBL7920131 | 0.84 | MTTP (0.48) | MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1099442-A2 | Methods of administering apo B-secretion/MTP inhibitors | Pfizer Products Inc. (US) | 2001-05-16 | — | — | EP | claimed |
| EP-1099442-A2 | Methods of administering apo B-secretion/MTP inhibitors | Pfizer Products Inc. (US) | 2001-05-16 | — | — | EP | disclosed |