Phosphoramidic Acid

Phosphoramidic Acid

SCHEMBL7925967

CCNCCN.NP(=O)(O)O

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.47
SAT1 P21673 1/20 0.46
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CYP2C19 P33261 2/20 0.42
GLA P06280 1/20 0.42
GABBR2 O75899 3/20 0.41
GABBR1 Q9UBS5 3/20 0.41
CA12 O43570 3/20 0.41
CA6 P23280 3/20 0.41
CA7 P43166 3/20 0.41
CA9 Q16790 3/20 0.41
CA14 Q9ULX7 3/20 0.41
CA5B Q9Y2D0 3/20 0.41
RECQL P46063 1/20 0.41
CYP1A2 P05177 2/20 0.40
TSHR P16473 2/20 0.40
GABRR1 P24046 1/20 0.40
BLM P54132 3/20 0.39
DRD3 P35462 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL14782319 0.93 ANPEP (0.48) ANPEPSAT1MEN1KMT2ACYP2C19
Medronic Acid SCHEMBL6368441 0.86 ANPEP (0.48) ANPEPSAT1MEN1KMT2ACYP2C19
Diethylamine SCHEMBL28794397 0.82 TP53 (0.50) ANPEPSAT1GABBR2GABBR1CA2
Diethylamine SCHEMBL28794398 0.82 TP53 (0.50) ANPEPSAT1GABBR2GABBR1CA2
SCHEMBL8624359 0.82 CA12 (0.60) SAT1MEN1KMT2ACYP2C19GLA
SCHEMBL199119 0.82
Formic Acid SCHEMBL27751208 0.80
Bicarbonate SCHEMBL525265 0.80 CYP2C19 (0.46) SAT1MEN1KMT2ACYP2C19GLA
Hydrochloric Acid SCHEMBL6266070 0.79
Hydrochloric Acid SCHEMBL6266059 0.79 KDM4E (0.59) MEN1KMT2ACYP2C19GLACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6331617-B1 USEFUL FOR BINDING TO NUCLEIC ACID TO INHIBIT OR ALTER GENE EXPRESSION UNIVERSITY OF IOWA RESEARCH FOUNDATION 2001-12-18 US claimed
US-5734040-A OLIGONUCLEOTIDES WITH ETHYLENEDIAMINE PHOSPHORAMIDATE FOR DNA UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 1998-03-31 US claimed
US-6331617-B1 USEFUL FOR BINDING TO NUCLEIC ACID TO INHIBIT OR ALTER GENE EXPRESSION UNIVERSITY OF IOWA RESEARCH FOUNDATION 2001-12-18 US disclosed