Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA6 | P23280 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10596405 | 0.92 | CYP2C19 (0.43) | CYP2C19MEN1KMT2AGLACA12 | |
| Acetic Acid SCHEMBL2637379 | 0.92 | CYP2C19 (0.43) | CYP2C19MEN1KMT2AGLACA12 | |
| Acetic Acid SCHEMBL28756444 | 0.88 | CA12 (0.50) | CYP2C19MEN1KMT2AGLACA12 | |
| Acetic Acid SCHEMBL21541922 | 0.88 | CA12 (0.50) | CYP2C19MEN1KMT2AGLACA12 | |
| Adipic Acid SCHEMBL28129525 | 0.86 | NFKB1 (0.56) | MEN1KMT2ARECQLCYP1A2TSHR | |
| Chloroacetic Acid SCHEMBL11377285 | 0.86 | TSHR (0.43) | CYP2C19MEN1KMT2AGLACA12 | |
| SCHEMBL199119 | 0.86 | — | — | |
| SCHEMBL8624359 | 0.86 | CA12 (0.60) | CYP2C19MEN1KMT2AGLACA12 | |
| Methacrylic Acid SCHEMBL1399536 | 0.84 | ALDH1A1 (0.38) | CYP2C19MEN1KMT2AGLACA12 | |
| Acrylic Acid SCHEMBL1399457 | 0.84 | LMNA (0.42) | CYP2C19MEN1KMT2AGLACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094692-B1 | LAMINATION PRINTING INK COMPRISING AN AQUEOUS DISPERSION COMPRISING POLYURETHANE | BASF SE (DE) | 2021-02-24 | — | — | EP | claimed |
| EP-3310864-B1 | WATER-BASED PRINTING INK COMPRISING AN AQUEOUS DISPERSED POLYURETHANE BINDER AND AN AQUEOUS DISPERSED POLY(METH)ACRYLATE BINDER | BASF SE (DE) | 2019-07-17 | — | — | EP | claimed |
| EP-2207829-B1 | DISPERSION ADHESIVES I | COVESTRO DEUTSCHLAND AG (DE) | 2018-04-11 | — | — | EP | claimed |
| EP-2207831-B1 | DISPERSION ADHESIVES II | COVESTRO DEUTSCHLAND AG (DE) | 2018-04-04 | — | — | EP | claimed |
| EP-1456267-B1 | AQUEOUS POLYURETHANE DISPERSIONS OBTAINED BY THE USE OF CESIUM SALTS | BASF SE (DE) | 2012-02-15 | — | — | EP | claimed |
| EP-3694944-B1 | PROTECTIVE FILMS MADE OF POLYOLEFIN SUPPORT MATERIAL, PRIMER AND RADIATION-CROSSLINKABLE HOT MELT ADHESIVE | BASF SE (DE) | 2024-04-24 | — | — | EP | disclosed |
| EP-4337706-A1 | ADHESIVES | Covestro Deutschland AG (DE) | 2024-03-20 | — | — | EP | disclosed |
| EP-4232492-A1 | USE OF RAW GEL IN FORMULATIONS ON THE BASIS OF POLYURETHANE DISPERSIONS | Covestro Deutschland AG (DE) | 2023-08-30 | — | — | EP | disclosed |
| EP-3856814-B1 | DISPERSION ADHESIVESTITLE | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-06-14 | — | — | EP | disclosed |
| EP-3874081-B1 | COMPOSITE COMPONENT COMPRISING A POLYCHLOROPRENE AND/OR POLYURETHANE BINDER | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-02-08 | — | — | EP | disclosed |
| EP-4029891-A1 | STORAGE-STABLE 1K SPRAY ADHESIVES BASED ON POLYURETHANE DISPERSIONS | Covestro Deutschland AG (DE) | 2022-07-20 | — | — | EP | disclosed |
| EP-4025637-A1 | DISPERSION ADHESIVES | Covestro Intellectual Property GmbH & Co. KG (DE) | 2022-07-13 | — | — | EP | disclosed |
| EP-0678537-A1 | Polyurethanes suitable as a coating agent | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-25 | — | — | EP | disclosed |
| EP-0629664-A1 | Aqueous polyurethane dispersions | BASF Aktiengesellschaft (DE) | 1994-12-21 | — | — | EP | disclosed |
| EP-0392352-B1 | Aqueous dispersions of high energy radiation curable polyurethanes | BASF AG (DE) | 1994-09-21 | — | — | EP | disclosed |
| EP-0605858-A1 | Process for the lowering of the PH-value of anionic polyurethane dispersions stabilized by carboxylate or sulfonate groups | BASF Aktiengesellschaft (DE) | 1994-07-13 | — | — | EP | disclosed |
| EP-0480251-A1 | Radiation curable aqueous binder dispersions | BASF Aktiengesellschaft (DE) | 1992-04-15 | — | — | EP | disclosed |
| EP-0272566-B1 | AQUEOUS POLYURETHANE ADHESIVE DISPERSIONS | BASF Aktiengesellschaft (DE) | 1992-03-11 | — | — | EP | disclosed |
| EP-0392352-A2 | Aqueous dispersions of high energy radiation curable polyurethanes | BASF Aktiengesellschaft (DE) | 1990-10-17 | — | — | EP | disclosed |
| EP-0272566-A2 | Aqueous polyurethane adhesive dispersions | BASF Aktiengesellschaft (DE) | 1988-06-29 | — | — | EP | disclosed |