Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.62 |
| ▸ | PPARA | Q07869 | 8/20 | 0.62 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 7/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7253863 | 1.00 | PPARG (0.62) | PPARGPPARAPPARDCACNA1BCACNA1H | |
| SCHEMBL7246043 | 0.90 | PPARG (0.59) | PPARGPPARAPPARDCACNA1BCACNA1H | |
| SCHEMBL6002497 | 0.88 | PPARA (0.62) | PPARGPPARAPPARDCACNA1BCACNA1H | |
| SCHEMBL16456491 | 0.83 | PPARG (0.44) | PPARGPPARAPPARD | |
| SCHEMBL7252703 | 0.82 | PPARA (0.57) | PPARGPPARAPPARDCACNA1BCACNA1H | |
| SCHEMBL6004280 | 0.80 | PPARA (0.57) | PPARGPPARAPPARD | |
| SCHEMBL6076525 | 0.80 | PPARG (0.48) | PPARGPPARAPPARD | |
| SCHEMBL7111821 | 0.79 | PPARG (0.46) | PPARGPPARAPPARD | |
| SCHEMBL7246699 | 0.79 | PPARA (0.58) | PPARGPPARAPPARD | |
| SCHEMBL7111084 | 0.79 | PPARG (0.46) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124808-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF NEW ANTIDIABETIC AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026200-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF NEW ANTIDIABETIC AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-05-11 | — | — | WO | disclosed |