Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.62 |
| ▸ | PPARG | P37231 | 11/20 | 0.62 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 6/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252703 | 0.90 | PPARA (0.57) | PPARAPPARGPPARDCACNA1BCACNA1H | |
| SCHEMBL6004280 | 0.89 | PPARA (0.57) | PPARAPPARGPPARD | |
| SCHEMBL7926847 | 0.88 | PPARG (0.62) | PPARAPPARGPPARDCACNA1BCACNA1H | |
| SCHEMBL7253863 | 0.88 | PPARG (0.62) | PPARAPPARGPPARDCACNA1BCACNA1H | |
| SCHEMBL6002512 | 0.86 | PPARG (0.46) | PPARAPPARGPPARD | |
| SCHEMBL7246699 | 0.84 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL5100738 | 0.82 | MAPT (0.45) | PPARAPPARGPPARD | |
| SCHEMBL7246043 | 0.82 | PPARG (0.59) | PPARAPPARGPPARDCACNA1BCACNA1H | |
| SCHEMBL7252700 | 0.80 | PPARG (0.57) | PPARAPPARGPPARDCACNA1BCACNA1H | |
| SCHEMBL8193712 | 0.78 | PPARA (0.54) | PPARAPPARGPPARDCACNA1BCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002537390-A | — | — | 2002-11-05 | — | — | JP | claimed |
| US-6440961-B1 | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-08-27 | — | — | US | claimed |
| US-20020077320-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION AND REDDY- CHEMINOR, INC. | 2002-06-20 | — | — | US | claimed |
| EP-1155006-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Dr. Reddy's Research Foundation (IN) | 2001-11-21 | — | — | EP | claimed |
| CN-1280575-A | Novel tricyclic compounds and their use as medicaments, process for their preparation and pharmaceutical compositions containing them | REDDY CHEMINOR INC (IN) | 2001-01-17 | — | — | CN | claimed |
| EP-1049684-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-08 | — | — | EP | claimed |
| WO-2000050414-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | DR.REDDY'S RESEARCH FOUNDATION (IN) | 2000-08-31 | — | — | WO | claimed |
| WO-1999019313-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-04-22 | — | — | WO | claimed |
| US-7119198-B2 | Tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2006-10-10 | — | — | US | disclosed |
| US-20060148793-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | REDDYS'S RESEARCH FOUNDATION | 2006-07-06 | — | — | US | disclosed |
| US-6939988-B1 | Tricyclic compounds and their use in medicine process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LIMITED (IN) | 2005-09-06 | — | — | US | disclosed |
| US-6608194-B1 | Hypolipidemic, antihyperglycemic, antiobesity and hypocholes-terolemic agents | DR. REDDY'S LABORATORIES LIMITED (IN) | 2003-08-19 | — | — | US | disclosed |
| US-6548666-B1 | Phenazine, phenoxazine, or phenothiazine derivatives; antilipemic, hypoglycemic, anticholesterol and antiobesity agents | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2003-04-15 | — | — | US | disclosed |
| US-6440961-B1 | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-08-27 | — | — | US | disclosed |
| US-20020077320-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION AND REDDY- CHEMINOR, INC. | 2002-06-20 | — | — | US | disclosed |
| EP-1155006-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | Dr. Reddy's Research Foundation (IN) | 2001-11-21 | — | — | EP | disclosed |
| EP-1049684-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-11-08 | — | — | EP | disclosed |
| WO-2000050414-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | DR.REDDY'S RESEARCH FOUNDATION (IN) | 2000-08-31 | — | — | WO | disclosed |
| US-6054453-A | HYPOLIPIDEMIC, ANTIHYPERGLYCEMIC USES. | REDD'S RESEARCH FOUNDATION (IN) | 2000-04-25 | — | — | US | disclosed |
| WO-1999019313-A1 | NOVEL TRICYCLIC COMPOUNDS AND THEIR USE IN MEDICINE; PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077320-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | LIPC, GPR119, CPT1A | PPARA 281/4885PPARG 102/4885PPARD 308/4885 |
| US-20060148793-A1 | Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them | LIPC, GPR119, CPT1A | PPARA 209/4885PPARG 73/4885PPARD 235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.