Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.43 |
| ▸ | MAOA | P21397 | 4/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917892 | 0.95 | NPC1 (0.41) | MAOBMAOAALDH2PPARDPPARA | |
| SCHEMBL7929108 | 0.92 | KMT2A (0.40) | MAOBMAOAALDH2PPARDPPARA | |
| SCHEMBL7921607 | 0.91 | MAOB (0.40) | MAOBMAOAALDH2PPARDPPARA | |
| SCHEMBL1390694 | 0.89 | MTNR1A (0.47) | MAOBMAOAALDH2PPARDPPARA | |
| SCHEMBL7922328 | 0.89 | PPARD (0.36) | MAOBMAOAALDH2PPARDPPARA | |
| SCHEMBL1390488 | 0.84 | ACACB (0.47) | MAOBMAOAALDH2PPARDPPARA | |
| SCHEMBL1390614 | 0.81 | ACACB (0.47) | PPARDPPARANPC1MTNR1AMAPT | |
| SCHEMBL7924953 | 0.81 | NPC1 (0.39) | MAOBPPARDPPARANPC1MAPT | |
| SCHEMBL1390645 | 0.80 | MTNR1A (0.46) | MAOBMAOAALDH2PPARDPPARA | |
| SCHEMBL1390926 | 0.80 | PPARD (0.46) | MAOBMAOAALDH2PPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010050445-A1 | BICYCLIC COMPOUND | 武田薬品工業株式会社 (JP) | 2010-05-06 | — | — | WO | disclosed |