SCHEMBL7927150

SCHEMBL7927150

CC(C)c1cccc(C(C)C)c1Nc1c(Cl)c2c(c(Cl)c1Nc1c(C(C)C)cccc1C(C)C)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.40
ANPEP P15144 1/20 0.39
DPP4 P27487 1/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
MAOA P21397 1/20 0.39
LMNA P02545 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB2 P47870 2/20 0.37
FAAH O00519 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRG2 P18507 1/20 0.37
PTGS1 P23219 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933027 0.94 SMN1; SMN2 (0.38) SMN1; SMN2ANPEPDPP4KMT2AMEN1
SCHEMBL7921537 0.84 SOAT1 (0.37)
SCHEMBL7921555 0.84 ANPEP (0.40) SMN1; SMN2ANPEPDPP4KMT2AMEN1
SCHEMBL7921293 0.82 ANPEP (0.38) SMN1; SMN2ANPEPDPP4KMT2AMEN1
SCHEMBL7927084 0.81 SMN1; SMN2 (0.38) SMN1; SMN2ANPEPDPP4KMT2AMEN1
SCHEMBL7930684 0.78 CLCN2 (0.39) SMN1; SMN2ANPEPDPP4KMT2AMEN1
SCHEMBL7930678 0.77 KMT2A (0.46) SMN1; SMN2ANPEPDPP4KMT2AMEN1
SCHEMBL7921215 0.75 CXCR2 (0.41) SMN1; SMN2KMT2AMEN1MAPTMAOA
SCHEMBL7921179 0.75 MEN1 (0.44) SMN1; SMN2ANPEPDPP4KMT2AMEN1
SCHEMBL7930624 0.75 KMT2A (0.36) SMN1; SMN2ANPEPDPP4KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed