SCHEMBL7930624

SCHEMBL7930624

CC(C)c1cccc(C(C)C)c1Nc1c(Nc2c(C(C)C)cccc2C(C)C)c(-c2ccccc2)c2c(c1-c1ccccc1)C(=O)c1c(O)ccc(S)c1C2=O

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.36
LMNA P02545 1/20 0.36
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
MAOA P21397 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
SOAT2 O75908 2/20 0.34
SOAT1 P35610 2/20 0.34
ANPEP P15144 1/20 0.33
DPP4 P27487 1/20 0.33
EGFR P00533 1/20 0.33
PIM1 P11309 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
LPAR1 Q92633 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7929925 0.78 SOAT1 (0.38) SOAT1
SCHEMBL8678112 0.78 MAPT (0.47) KMT2ALMNAMEN1MAPTMAOA
SCHEMBL8677763 0.76 CXCR2 (0.40) KMT2ALMNAMEN1MAPTMAOA
SCHEMBL7921555 0.76 ANPEP (0.40) KMT2ALMNAMEN1MAPTMAOA
SCHEMBL7927084 0.75 SMN1; SMN2 (0.38) KMT2ALMNAMEN1MAPTMAOA
SCHEMBL7927150 0.75 SMN1; SMN2 (0.40) KMT2ALMNAMEN1MAPTMAOA
SCHEMBL7921293 0.74 ANPEP (0.38) KMT2ALMNAMEN1MAPTMAOA
SCHEMBL7933027 0.73 SMN1; SMN2 (0.38) KMT2ALMNAMEN1MAPTMAOA
SCHEMBL7930678 0.70 KMT2A (0.46) KMT2ALMNAMEN1MAPTMAOA
SCHEMBL28980492 0.69 GABRA1 (0.41) KMT2ALMNAMAPTGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed