SCHEMBL7927463

SCHEMBL7927463

CCCCCC/C=C(\F)CO

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.47
TSHR P16473 4/20 0.41
LMNA P02545 3/20 0.40
HSD17B10 Q99714 2/20 0.40
ALDH1A1 P00352 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
FAAH O00519 2/20 0.37
TRPV1 Q8NER1 1/20 0.37
GMNN O75496 1/20 0.36
USP2 O75604 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
ALOX15 P16050 1/20 0.36
APEX1 P27695 1/20 0.36
CYP2C19 P33261 1/20 0.36
RECQL P46063 1/20 0.36
BLM P54132 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14721308 1.00 EP300 (0.47) EP300TSHRLMNAHSD17B10ALDH1A1
SCHEMBL14721307 1.00 EP300 (0.47) EP300TSHRLMNAHSD17B10ALDH1A1
SCHEMBL7927464 1.00 EP300 (0.47) EP300TSHRLMNAHSD17B10ALDH1A1
SCHEMBL7647914 0.98 EP300 (0.43) EP300TSHRLMNAHSD17B10ALDH1A1
SCHEMBL7647916 0.98 EP300 (0.43) EP300TSHRLMNAHSD17B10ALDH1A1
SCHEMBL20235219 0.91
SCHEMBL23048256 0.82 EP300 (0.47) EP300LMNAHSD17B10MEN1KMT2A
SCHEMBL7067072 0.82 EP300 (0.47) EP300LMNAHSD17B10MEN1KMT2A
SCHEMBL7067069 0.82 EP300 (0.47) EP300LMNAHSD17B10MEN1KMT2A
SCHEMBL29015770 0.82 EP300 (0.47) EP300LMNAHSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0811596-B1 Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds BASF AG (DE) 2001-07-25 EP claimed
US-6262319-B1 BROMINATION OF THE CORRESPONDING ALCOHOL COMPOUND AMERICAN CYANAMID CO. 2001-07-17 US claimed
US-5892131-A Process for the preparation of pesticidal fluoroolefin compounds AMERICAN CYANAMID COMPANY (US) 1999-04-06 US claimed
EP-0811596-A1 Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds American Cyanamid Company (US) 1997-12-10 EP claimed
EP-0811596-B1 Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds BASF AG (DE) 2001-07-25 EP disclosed
US-6262319-B1 BROMINATION OF THE CORRESPONDING ALCOHOL COMPOUND AMERICAN CYANAMID CO. 2001-07-17 US disclosed
US-5892131-A Process for the preparation of pesticidal fluoroolefin compounds AMERICAN CYANAMID COMPANY (US) 1999-04-06 US disclosed
EP-0811596-A1 Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds American Cyanamid Company (US) 1997-12-10 EP disclosed