SCHEMBL7067072

SCHEMBL7067072

CCCCCCC=C(F)CCCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.47
FAAH O00519 5/20 0.45
TERT O14746 3/20 0.45
PTPN1 P18031 3/20 0.45
PPARG P37231 3/20 0.45
PPARD Q03181 3/20 0.45
PPARA Q07869 3/20 0.45
CYP1A2 P05177 2/20 0.45
MAPT P10636 2/20 0.45
CYP2C19 P33261 2/20 0.45
BLM P54132 2/20 0.45
HSD17B10 Q99714 2/20 0.45
FABP4 P15090 2/20 0.45
KMT2A Q03164 2/20 0.45
GMNN O75496 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
CYP2C9 P11712 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29015770 1.00 EP300 (0.47) EP300FAAHTERTPTPN1PPARG
SCHEMBL23048256 1.00 EP300 (0.47) EP300FAAHTERTPTPN1PPARG
SCHEMBL28332222 1.00 EP300 (0.47) EP300FAAHTERTPTPN1PPARG
SCHEMBL7067069 1.00 EP300 (0.47) EP300FAAHTERTPTPN1PPARG
SCHEMBL11452704 0.87 PPARG (0.62) FAAHTERTPTPN1PPARGPPARD
Silver SCHEMBL11452703 0.86 FABP3 (0.64) EP300PPARGPPARAFABP3
Silver SCHEMBL11452705 0.86 FABP3 (0.64) EP300PPARGPPARAFABP3
SCHEMBL7927463 0.82 EP300 (0.47) EP300FAAHTERTCYP1A2MAPT
SCHEMBL7645118 0.82 CES2 (0.41) PTPN1PPARGPPARDPPARAHSD17B10
SCHEMBL7927464 0.82 EP300 (0.47) EP300FAAHTERTCYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1202948-B1 PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AG (DE) 2003-12-10 EP claimed
EP-1131273-B1 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AG (DE) 2003-10-22 EP claimed
EP-1159241-B1 PROCESSES FOR THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AG (DE) 2003-08-20 EP claimed
EP-1202948-A1 PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2002-05-08 EP claimed
US-6342642-B1 DEHYDROXYLATION OF HALOBUTENOL COMPOUNDS TO FORM BUTADIENES BASF AKTIENGESELLSCHAFT (DE) 2002-01-29 US claimed
EP-1159241-A1 PROCESSES FOR THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-12-05 EP claimed
US-6291721-B1 REACTING 2-ARYL ALDEHYDE COMPOUND WITH ALCOHOL OR HEATING ACETAL COMPOUND IN PRESENCE OF APROTIC SOLVENT TO PRODUCE2-ARYLVINYL ETHER COMPOUND AMERICAN CYANAMID CO. 2001-09-18 US claimed
EP-1131273-A1 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2001-09-12 EP claimed
WO-2001012578-A1 PROCESSES FOR THE PREPARATION OF 2-ARYLVINYL ALKYL ETHER AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 2001-02-22 WO claimed
WO-2000029362-A1 1,4-DIARYL-2-FLUORO-1-BUTEN-3-OL COMPOUNDS AND THEIR USE IN THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2000-05-25 WO claimed
WO-2000029363-A1 PROCESSES FOR THE PREPARATION OF 1,4-DIARYL-2-FLUORO-1,3-BUTADIENE AND 1,4-DIARYL-2-FLUORO-2-BUTENE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 2000-05-25 WO claimed
CN-1215030-C 1,4-diaryl-2-fluoro-2-butene insecticidal and acaricidal agents AMERICAN CYANAMID CO (US) 2005-08-17 CN disclosed
CN-1210241-C 1,4-diaryl-2-fluoro-1-buten-3-ol compounds and their use in the preparation of 1,4-diaryl-2-fluoro-1,3-butadiene and 1,4-diaryl-2-fluoro-2-butene compounds BASF AG (DE) 2005-07-13 CN disclosed
CN-1210241-C 1,4-diaryl-2-fluoro-1-buten-3-ol compounds and their use in the preparation of 1,4-diaryl-2-fluoro-1,3-butadiene and 1,4-diaryl-2-fluoro-2-butene compounds BASF AG (DE) 2005-07-13 CN disclosed
US-6776996-B2 Pesticidal matrices BASF AKTIENGESELLSCHAFT (DE) 2004-08-17 US disclosed
EP-0811593-A1 1,4-diaryl-2-fluoro-2-butene insecticidal and acaricidal agents American Cyanamid Company (US) 1997-12-10 EP disclosed
EP-0811593-A1 1,4-diaryl-2-fluoro-2-butene insecticidal and acaricidal agents American Cyanamid Company (US) 1997-12-10 EP disclosed
EP-0811596-A1 Process and intermediate compounds for the preparation of pesticidal fluoroolefin compounds American Cyanamid Company (US) 1997-12-10 EP disclosed
EP-0811593-A1 1,4-diaryl-2-fluoro-2-butene insecticidal and acaricidal agents American Cyanamid Company (US) 1997-12-10 EP disclosed
CN-1167105-A 1,4-diaryl-2-fluoro-2-butene insecticidal and acaricidal agents AMERICAN CYANAMID CO (US) 1997-12-10 CN disclosed