Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | TSHR | P16473 | 6/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL65261 | 0.74 | ALDH1A1 (1.00) | ALDH1A1TSHRALOX15HSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL379126 | 0.71 | ALDH1A1 (0.92) | ALDH1A1TSHRALOX15HSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL2443748 | 0.71 | ALDH1A1 (0.92) | ALDH1A1TSHRALOX15HSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL379125 | 0.71 | ALDH1A1 (0.92) | ALDH1A1TSHRALOX15HSD17B10MEN1 | |
| Ammonia Solution, Strong SCHEMBL27868785 | 0.71 | ALDH1A1 (0.92) | ALDH1A1TSHRALOX15HSD17B10MEN1 | |
| SCHEMBL30634059 | 0.70 | ALDH1A1 (0.42) | ALDH1A1TSHRALOX15HSD17B10MEN1 | |
| SCHEMBL12359283 | 0.68 | ALDH1A1 (0.52) | ALDH1A1TSHRALOX15HSD17B10TDP1 | |
| SCHEMBL7076748 | 0.68 | ALDH1A1 (0.85) | ALDH1A1TSHRALOX15HSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL7080476 | 0.68 | ALDH1A1 (0.85) | ALDH1A1TSHRALOX15HSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL21799403 | 0.68 | ALDH1A1 (0.85) | ALDH1A1TSHRALOX15HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001527390-A | — | — | 2001-12-25 | — | — | JP | claimed |
| EP-1011655-A1 | INHIBITORS OF LEADERLESS PROTEIN EXPORT | Ciblex Corporation (US) | 2000-06-28 | — | — | EP | claimed |
| WO-1998037880-A1 | INHIBITORS OF LEADERLESS PROTEIN EXPORT | CIBLEX CORPORATION (US) | 1998-09-03 | — | — | WO | claimed |