Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7917921 | 0.87 | TAAR1 (0.47) | TAAR1ADRA2ABACE1LRRK2 | |
| SCHEMBL7918039 | 0.87 | TAAR1 (0.47) | TAAR1ADRA2ABACE1LRRK2 | |
| SCHEMBL7930026 | 0.82 | TAAR1 (0.34) | TAAR1ADRA2A | |
| SCHEMBL12203467 | 0.80 | TAAR1 (0.40) | TAAR1ADRA2ABACE1LRRK2 | |
| SCHEMBL7919354 | 0.79 | TAAR1 (0.36) | TAAR1ADRA2ABACE1 | |
| SCHEMBL7927172 | 0.79 | TAAR1 (0.54) | TAAR1ADRA2ABACE1LRRK2 | |
| SCHEMBL12203505 | 0.75 | TAAR1 (0.36) | TAAR1ADRA2A | |
| SCHEMBL12203502 | 0.75 | TAAR1 (0.36) | TAAR1ADRA2A | |
| SCHEMBL12203955 | 0.73 | TAAR1 (0.49) | TAAR1ADRA2ABACE1 | |
| SCHEMBL12203961 | 0.73 | TAAR1 (0.49) | TAAR1ADRA2ABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042473-A1 | BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |