Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14134575 | 0.86 | TAAR1 (0.36) | TAAR1ADRA2AALDH1A1ADRA1DADRA1A | |
| SCHEMBL7924481 | 0.84 | TAAR1 (0.51) | TAAR1ADRA2AALDH1A1ADRA1DADRA1A | |
| SCHEMBL7927717 | 0.82 | TAAR1 (0.32) | TAAR1ADRA2A | |
| SCHEMBL7919354 | 0.82 | TAAR1 (0.36) | TAAR1ADRA2A | |
| SCHEMBL12203506 | 0.79 | GRM5 (0.32) | ALDH1A1 | |
| SCHEMBL14134558 | 0.78 | TAAR1 (0.43) | TAAR1ADRA2AADRA1DADRA1AADRA1B | |
| SCHEMBL14134568 | 0.78 | TAAR1 (0.43) | TAAR1ADRA2AADRA1DADRA1AADRA1B | |
| SCHEMBL12204054 | 0.77 | TAAR1 (0.40) | TAAR1ADRA2AALDH1A1 | |
| SCHEMBL7917869 | 0.76 | ADRA2A (0.60) | TAAR1ADRA2AADRA1DADRA1AADRA1B | |
| SCHEMBL7917896 | 0.76 | ADRA2A (0.60) | TAAR1ADRA2AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010042473-A1 | BIARYL SPIROAMINOOXAZOLINE ANALOGUES AS ALPHA2C ADRENERGIC RECEPTOR MODULATORS | SCHERING CORPORATION (US) | 2010-04-15 | — | — | WO | disclosed |