Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28965718 | 0.83 | SMYD3 (0.50) | SRD5A1SRD5A2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL29267730 | 0.82 | SMYD3 (0.49) | SRD5A1SRD5A2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24233407 | 0.79 | SMN1; SMN2 (0.60) | SRD5A1SRD5A2MAPTRAB9ALMNA | |
| SCHEMBL1965892 | 0.77 | SMYD3 (0.60) | MAPTLMNAALDH1A1KMT2APKM | |
| SCHEMBL31348187 | 0.77 | SMYD3 (0.60) | MAPTLMNAALDH1A1KMT2APKM | |
| SCHEMBL1115098 | 0.76 | MAPT (0.63) | SRD5A1SRD5A2MAPTRAB9ALMNA | |
| SCHEMBL30935799 | 0.76 | MAPT (0.63) | SRD5A1SRD5A2MAPTRAB9ALMNA | |
| SCHEMBL19357202 | 0.74 | MAPT (0.60) | MAPTRAB9ALMNAALDH1A1NPC1 | |
| SCHEMBL26630607 | 0.74 | TMEM97 (0.56) | SRD5A1SRD5A2MAPTRAB9ALMNA | |
| SCHEMBL11319049 | 0.74 | SMYD3 (0.51) | LMNAALDH1A1KMT2APKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6228868-B1 | ANTICARCINOGENIC AND ANTITUMOR AGENTS | ABBOTT LABORATORIES | 2001-05-08 | — | — | US | disclosed |
| WO-2000006556-A1 | SUBSTITUTED OXAZOLINES AS ANTIPROLIFERATIVE AGENTS | ABBOTT LABORATORIES (US) | 2000-02-10 | — | — | WO | disclosed |