SCHEMBL7928142

SCHEMBL7928142

C=Cc1ccccc1OC1CCCC(=O)N1C

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 19/20 0.39
HCRTR2 O43614 19/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3869203 0.74 PDE4A (0.40) HCRTR1HCRTR2KMT2A
SCHEMBL7928086 0.73 HPGD (0.38) HCRTR2MEN1KMT2A
SCHEMBL15496945 0.69 HPGD (0.40) KMT2A
SCHEMBL7928144 0.69 SRD5A1 (0.43) HCRTR1HCRTR2
SCHEMBL1397150 0.67 HPGD (0.42)
SCHEMBL7937789 0.66 KMT2A (0.42) MEN1KMT2A
SCHEMBL7934730 0.66 MEN1 (0.40) MEN1KMT2A
SCHEMBL17968576 0.65 MCHR1 (0.44)
SCHEMBL1240108 0.64 KDM4E (0.54) HCRTR1HCRTR2MEN1KMT2A
SCHEMBL6438027 0.63 CYP2C19 (0.34) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6284863-B1 REACTED WITH UNSATURATED AMIDES THAT MAY BE CYCLIC, E.G., N-VINYL-2-PYRROLIDONE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-09-04 US disclosed