Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7928142 | 0.73 | HCRTR1 (0.39) | KMT2AMEN1HCRTR2 | |
| SCHEMBL289801 | 0.71 | ALDH1A1 (0.43) | L3MBTL1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL10036489 | 0.68 | CHRM2 (0.37) | TACR1 | |
| SCHEMBL15496945 | 0.68 | HPGD (0.40) | HPGDKMT2AALDH1A1 | |
| SCHEMBL27744258 | 0.67 | CYP2C19 (0.45) | SMN1; SMN2NPC1RAB9APOLBTACR1 | |
| Tannin Pyrogallol SCHEMBL11122368 | 0.67 | SLC18A3 (0.46) | HPGDSMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL1397150 | 0.67 | HPGD (0.42) | HPGDALDH1A1 | |
| SCHEMBL30706195 | 0.66 | PTGS2 (0.52) | HPGDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL58004 | 0.66 | PTGS2 (0.52) | HPGDNPC1RAB9AKMT2AMEN1 | |
| SCHEMBL1196325 | 0.65 | CHRM2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284863-B1 | REACTED WITH UNSATURATED AMIDES THAT MAY BE CYCLIC, E.G., N-VINYL-2-PYRROLIDONE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-09-04 | — | — | US | disclosed |