SCHEMBL7928254

SCHEMBL7928254

O=C1c2c(O)ccc(O)c2C(=O)c2c(F)c(Nc3ccccc3)c(F)c(F)c21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 11/20 0.45
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
MAPT P10636 3/20 0.43
MAOA P21397 1/20 0.43
DHODH Q02127 1/20 0.39
NPC1 O15118 1/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CSNK2A2 P19784 1/20 0.38
CSNK2B P67870 1/20 0.38
CSNK2A1 P68400 1/20 0.38
CSNK2A3 Q8NEV1 1/20 0.38
CYP3A4 P08684 2/20 0.38
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7930883 0.93 CXCR2 (0.47) CXCR2MEN1KMT2AMAPTMAOA
SCHEMBL6651237 0.83 MAPT (0.51) CXCR2MEN1KMT2AMAPTMAOA
SCHEMBL7929772 0.82 HIF1A (0.42) LMNAMAPK1CSNK2A2CSNK2BCSNK2A1
SCHEMBL7930030 0.82 CA12 (0.40) CXCR2MEN1KMT2AMAPTMAOA
SCHEMBL7921224 0.82 CA12 (0.40) CXCR2MEN1KMT2AMAPTMAOA
SCHEMBL7930796 0.81 CXCR2 (0.44) CXCR2MAPTLMNACYP3A4TSHR
SCHEMBL7921197 0.81 MAPT (0.43) MEN1KMT2AMAPTNPC1LMNA
SCHEMBL7928605 0.81 MEN1 (0.40) MEN1KMT2AMAPTNPC1MAPK1
SCHEMBL7929862 0.80 CYP3A4 (0.49) CXCR2MEN1KMT2AMAPTMAPK1
SCHEMBL7927100 0.80 MEN1 (0.57) MEN1KMT2AMAPTDHODHMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8151531-A None JP disclosed
JP-6279694-A None JP disclosed
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
JP-H08151531-A QUINIZARIN DERIVATIVE COMPOUND, ITS PRODUCTION AND USE NIPPON SHOKUBAI CO LTD 1996-06-11 JP disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed
JP-H06279694-A NEW QUINIZARIN-BASED COMPOUND, PRODUCTION THEREOF AND VISIBLE LIGHT ABSORBER CONTAINING THE SAME NIPPON SHOKUBAI CO LTD 1994-10-04 JP disclosed