SCHEMBL7930883

SCHEMBL7930883

O=C1c2c(O)ccc(O)c2C(=O)c2c(F)c(Nc3ccccc3)c(Nc3ccccc3)c(F)c21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 10/20 0.47
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
MAPT P10636 3/20 0.46
MAOA P21397 1/20 0.46
DHODH Q02127 1/20 0.41
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
CSNK2A1 P68400 1/20 0.40
CSNK2A3 Q8NEV1 1/20 0.40
TDP1 Q9NUW8 2/20 0.40
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP3A4 P08684 2/20 0.40
TSHR P16473 2/20 0.40
HPGD P15428 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928254 0.93 CXCR2 (0.45) CXCR2MEN1KMT2AMAPTMAOA
SCHEMBL7930030 0.84 CA12 (0.40) CXCR2MEN1KMT2AMAPTMAOA
SCHEMBL7921224 0.84 CA12 (0.40) CXCR2MEN1KMT2AMAPTMAOA
SCHEMBL7930584 0.84 HDAC1 (0.40) CXCR2MEN1KMT2AMAPTTDP1
SCHEMBL21816966 0.82 MAPT (0.54) CXCR2MEN1KMT2AMAPTMAOA
SCHEMBL7930029 0.81 ADAMTS5 (0.43) CXCR2MEN1KMT2AMAPTNPC1
SCHEMBL7930664 0.80 MAPT (0.39) CXCR2MEN1KMT2AMAPTMAOA
SCHEMBL7921288 0.80 MAPT (0.46) MEN1KMT2AMAPTTDP1NPC1
SCHEMBL7933227 0.80 CXCR2 (0.46) CXCR2MAPTLMNACYP3A4TSHR
SCHEMBL7928305 0.80 MEN1 (0.42) MEN1KMT2AMAPTTDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed