SCHEMBL7928272

SCHEMBL7928272

CCCCOc1c(Nc2c(Cl)cccc2Cl)c(Nc2c(Cl)cccc2Cl)c(F)c2c1C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.34
CA12 O43570 3/20 0.34
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA4 P22748 3/20 0.34
CA9 Q16790 3/20 0.34
KCNH2 Q12809 1/20 0.34
CCR4 P51679 1/20 0.32
CTSG P08311 2/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
POLH Q9Y253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928316 0.96 ELANE (0.34) ELANECA12CA1CA2CA4
SCHEMBL7930665 0.94 MAPK14 (0.36) ELANEKCNH2
SCHEMBL7928355 0.92 ELANE (0.37) ELANECA12CA1CA2CA4
SCHEMBL7929756 0.90 MAPK14 (0.35) ELANECTSGALDH1A1
SCHEMBL7930388 0.88 ELANE (0.37) ELANECTSGMEN1KMT2AEGFR
SCHEMBL7927144 0.88 ELANE (0.35) ELANECTSGMEN1NPC1ALDH1A1
SCHEMBL7929940 0.87 ELANE (0.34) ELANECA12CA1CA2CA9
SCHEMBL7921360 0.86 MAPK14 (0.36) ELANECTSG
SCHEMBL7928267 0.86 ELANE (0.37) ELANECTSGMEN1NPC1ALDH1A1
SCHEMBL7928247 0.86 ELANE (0.41) ELANECTSG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed