SCHEMBL7928267

SCHEMBL7928267

CCCCOc1c(Nc2c(CCC)cccc2CCC)c(Nc2c(CCC)cccc2CCC)c(F)c2c1C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 9/20 0.37
CTSG P08311 5/20 0.37
MTNR1A P48039 2/20 0.32
PPARD Q03181 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
POLH Q9Y253 1/20 0.31
EGFR P00533 1/20 0.31
PIM1 P11309 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928247 0.96 ELANE (0.41) ELANECTSGMTNR1ACNR2
SCHEMBL7927144 0.94 ELANE (0.35) ELANECTSGMTNR1AMEN1NPC1
SCHEMBL7930360 0.89 ELANE (0.37) ELANECTSGCNR2
SCHEMBL7928272 0.86 ELANE (0.34) ELANECTSGMEN1NPC1ALDH1A1
SCHEMBL7929940 0.86 ELANE (0.34) ELANECTSGMEN1NPC1ALDH1A1
SCHEMBL7930686 0.86 ELANE (0.38) ELANECTSGMEN1NPC1ALDH1A1
SCHEMBL7933042 0.85 ELANE (0.48) ELANECTSGMEN1MAPTKMT2A
SCHEMBL7927099 0.84 SOAT1 (0.37)
SCHEMBL7929731 0.84 ELANE (0.43) ELANECTSGMEN1ALDH1A1MAPT
SCHEMBL7933215 0.84 FAAH (0.38) ELANECTSGCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed