Acetonitrile

Acetonitrile

SCHEMBL7928496

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nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Acetonitrile. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetonitrile SCHEMBL2370865 0.94
Acetonitrile SCHEMBL1483508 0.94 TSHR (0.33) TSHRALDH1A1
Acetonitrile SCHEMBL1148960 0.94
Acetonitrile SCHEMBL20357991 0.88
Acetonitrile SCHEMBL79033 0.88
Acetonitrile SCHEMBL6239339 0.88 TSHR (0.31) TSHRALDH1A1
Acetonitrile SCHEMBL10561604 0.88
Acetonitrile SCHEMBL10790879 0.88
Acetonitrile SCHEMBL10898984 0.88
Acetonitrile SCHEMBL19182435 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0828768-B1 HOMOPOLYMERS AND COPOLYMERS OF CATIONICALLY POLYMERIZABLE MONOMERS AND METHOD OF THEIR PREPARATION GOODRICH CO B F (US) 2001-04-18 EP claimed
US-9468898-B2 Reactor, reaction method, and reaction product KOBE STEEL, LTD. (JP) 2016-10-18 US disclosed
US-20150314258-A1 REACTOR, REACTION METHOD, AND REACTION PRODUCT KABUSHIKI KAISHA KOBE SEIKO SHO (KOBE STEEL, LTD.) (JP) 2015-11-05 US disclosed
US-5569730-A HAVING TERMINAL END GROUP DERIVED FROM CHAIN TRANSFER AGENT CONTAINING TERMINAL OLEFINIC DOUBLE BOND THE B. F. GOODRICH COMPANY (US) 1996-10-29 US disclosed