Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 6/20 | 0.51 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5673442 | 0.84 | SLC22A12 (0.56) | ARF2 | |
| SCHEMBL27694543 | 0.74 | GRM5 (0.51) | ARNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL15164008 | 0.73 | GRM5 (0.51) | ARNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL14339782 | 0.73 | GRM5 (0.59) | RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL14218089 | 0.73 | GRM5 (0.59) | RAB9ASMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4081819 | 0.72 | GRM5 (0.50) | ARNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL13841458 | 0.72 | GRM5 (0.62) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1072784 | 0.72 | GRM5 (0.62) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL1460568 | 0.72 | TTK (0.52) | ARNPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL28235227 | 0.71 | GRM5 (0.55) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235778-B1 | ANTICOAGULANTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2001-05-22 | — | — | US | disclosed |