SCHEMBL7928584

SCHEMBL7928584

COC(Cc1ccc(OCCN2c3ccccc3Oc3ccccc32)cc1)C(=O)O

nearest known ligand 0.81

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.81
PPARA Q07869 16/20 0.81
PPARD Q03181 10/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5347950 0.90 PPARG (0.70) PPARGPPARAPPARD
Ragaglitazar SCHEMBL29369224 0.89 PPARA (1.00) PPARGPPARAPPARD
Ragaglitazar SCHEMBL4822459 0.89 PPARA (1.00) PPARGPPARAPPARD
Ragaglitazar SCHEMBL676872 0.89 PPARA (1.00) PPARGPPARAPPARD
Ragaglitazar SCHEMBL682732 0.89 PPARA (1.00) PPARGPPARAPPARD
SCHEMBL6002510 0.89 PPARG (0.77) PPARGPPARA
SCHEMBL5424404 0.89 PPARG (0.64) PPARGPPARAPPARD
SCHEMBL7534341 0.88 PPARG (0.64) PPARGPPARAPPARD
SCHEMBL6002537 0.88 PPARG (0.85) PPARGPPARAPPARD
SCHEMBL7514537 0.88 PPARG (0.74) PPARGPPARAPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1124808-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF NEW ANTIDIABETIC AGENTS DR. REDDY'S RESEARCH FOUNDATION (IN) 2001-08-22 EP disclosed
WO-2000026200-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF NEW ANTIDIABETIC AGENTS DR. REDDY'S RESEARCH FOUNDATION (IN) 2000-05-11 WO disclosed