SCHEMBL7928622

SCHEMBL7928622

C[Ti](C)(=[SiH2])(OC(=O)c1cccc2ccccc12)(OC(=O)c1cccc2ccccc12)(C1=CC=CC1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
HTR7 P34969 1/20 0.33
HTR2B P41595 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
HRH3 Q9Y5N1 1/20 0.32
HPGD P15428 2/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
KCNH2 Q12809 1/20 0.32
ADRB2 P07550 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7919532 0.89 KMT2A (0.39) KMT2APOLBGAAHTR7HTR2B
SCHEMBL8158143 0.85 NPC1 (0.36) KMT2AHTR7HTR2BNPC1RAB9A
SCHEMBL7925780 0.84 RAB9A (0.40) HTR7HTR2BNPC1RAB9ACYP1A2
SCHEMBL7925739 0.84 KMT2A (0.40) KMT2APOLBGAANPC1RAB9A
SCHEMBL7930965 0.83 MAPT (0.34) GAAHTR7HTR2BNPC1RAB9A
SCHEMBL7925497 0.83 NPC1 (0.35) HTR7HTR2BNPC1RAB9A
SCHEMBL7928734 0.82 NPC1 (0.36) HTR7HTR2BNPC1RAB9A
SCHEMBL7919108 0.82 NPC1 (0.36) HTR7HTR2BNPC1RAB9A
SCHEMBL7930302 0.81 NPC1 (0.35) HTR7HTR2BNPC1RAB9A
SCHEMBL7925609 0.81 NPC1 (0.37) HTR7HTR2BNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0867454-B1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN CO (JP) 2001-03-21 EP disclosed
US-6075102-A Polymerization catalyst and process for producing polymers IDEMITSU KOSAN CO., LTD. (JP) 2000-06-13 US disclosed
EP-0867454-A1 POLYMERIZATION CATALYST AND PROCESS FOR PRODUCING POLYMERS IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-30 EP disclosed