Biphenyl

Biphenyl

SCHEMBL7928631

C=CCc1ccccc1-c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.52
GABRA1 P14867 2/20 0.52
GABRB2 P47870 2/20 0.52
KMT2A Q03164 1/20 0.44
AKR1B1 P15121 1/20 0.44
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
AURKA O14965 1/20 0.39
DAPK3 O43293 1/20 0.39
MAP4K4 O95819 1/20 0.39
RET P07949 1/20 0.39
IGF1R P08069 1/20 0.39
MET P08581 1/20 0.39
PIM1 P11309 1/20 0.39
LTK P29376 1/20 0.39
KDR P35968 1/20 0.39
MAPK8 P45983 1/20 0.39
MAPK9 P45984 1/20 0.39
CDK8 P49336 1/20 0.39
CLK2 P49760 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170787 0.98 DPP4 (0.54) DPP4GABRA1GABRB2KMT2AAKR1B1
SCHEMBL28758160 0.96 DPP4 (0.52) DPP4GABRA1GABRB2KMT2AAKR1B1
Water SCHEMBL821345 0.96 DPP4 (0.52) DPP4GABRA1GABRB2KMT2AAKR1B1
SCHEMBL27684898 0.96 DPP4 (0.52) DPP4GABRA1GABRB2KMT2AAKR1B1
SCHEMBL6537109 0.94 GABRA1 (0.59) DPP4GABRA1GABRB2KMT2AAKR1B1
Cyanide SCHEMBL29219587 0.92 GABRA1 (0.48) DPP4GABRA1GABRB2KMT2AAKR1B1
SCHEMBL28267634 0.92 GABRA1 (0.48) DPP4GABRA1GABRB2KMT2AAKR1B1
SCHEMBL27886719 0.92 GABRA1 (0.47) DPP4GABRA1GABRB2KMT2AAKR1B1
SCHEMBL27986059 0.90 GABRA1 (0.47) DPP4GABRA1GABRB2KMT2AAKR1B1
SCHEMBL3125568 0.90 GABRA1 (0.50) DPP4GABRA1GABRB2KMT2AAKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1071324-A1 BLOOMING TYPE GERMICIDAL HARD-SURFACE CLEANERS Reckitt Benckiser Inc. (US) 2001-01-31 EP disclosed
EP-1034245-A1 CONCENTRATED LIQUID CLEANER FOR HARD SURFACES Reckitt Benckiser Inc. (US) 2000-09-13 EP disclosed
US-6100231-A CONCENTRATED LIQUID CLEANING COMPOSITIONS NORMALLY DILUTED IN A LARGER VOLUME OF WATER COMPRISING PINE OIL, ORGANIC SOLVENT, A BINARY CO-SOLVENT SYSTEM OFAN ALKYL BIPHENYL SOLVENT AND A COSOLVENT AND AN AMINE OXIDE SURFACTANT RECKITT & COLMAN INC. (US) 2000-08-08 US disclosed
US-6075002-A Biphenyl based solvents in blooming type germicidal hard surface cleaners RECKITT & COLMAN INC. (US) 2000-06-13 US disclosed
WO-1999052361-A1 BLOOMING TYPE GERMICIDAL HARD-SURFACE CLEANERS RECKITT BENCKISER INC. (US) 1999-10-21 WO disclosed
WO-1999028428-A1 CONCENTRATED LIQUID CLEANER FOR HARD SURFACES RECKITT BENCKISER INC. (US) 1999-06-10 WO disclosed