Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5428734 | 0.79 | DPP4 (0.41) | DPP4AOC3IDO1TDO2SLC6A4 | |
| SCHEMBL27966124 | 0.79 | DPP4 (0.41) | DPP4AOC3IDO1TDO2DPP8 | |
| SCHEMBL264970 | 0.79 | ADRB2 (0.50) | AOC3IDO1TDO2SLC6A4SLC6A2 | |
| SCHEMBL4628662 | 0.79 | DPP4 (0.41) | DPP4AOC3IDO1TDO2SLC6A4 | |
| SCHEMBL268751 | 0.79 | ESR1 (0.43) | ALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL25187548 | 0.79 | DPP4 (0.41) | DPP4AOC3IDO1TDO2SLC6A4 | |
| SCHEMBL265124 | 0.79 | PDE2A (0.39) | IDO1 | |
| SCHEMBL266309 | 0.78 | SCN4A (0.45) | DPP4 | |
| SCHEMBL11555282 | 0.77 | AOC3 (0.36) | AOC3IDO1TDO2MAOAMAOB | |
| SCHEMBL265653 | 0.76 | CYP1A2 (0.59) | AOC3MAOAMAOBSLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6239071-B1 | DIAMINO-1,3,5-TRIAZINE COMPOUND | HOECHT SCHERING AGREVO GMBH (DE) | 2001-05-29 | — | — | US | disclosed |