Phenylglycine

Phenylglycine

SCHEMBL7929007

CN(CC(=O)O)c1ccccc1.N[C@@H](C(=O)O)c1ccccc1

nearest known ligand 0.41

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Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.40
CYP2D6 P10635 1/20 0.39
OPRK1 P41145 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NLRP3 Q96P20 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
GRM2 Q14416 1/20 0.37
GRM3 Q14832 1/20 0.37
GAA P10253 1/20 0.37
GABBR2 O75899 1/20 0.37
GABBR1 Q9UBS5 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL196635 0.83 KMT2A (0.49) RXFP1MEN1KMT2ANLRP3
SCHEMBL11973878 0.81 KMT2A (0.47) RXFP1MEN1KMT2ANLRP3
Ethane SCHEMBL7405342 0.81 KMT2A (0.47) RXFP1MEN1KMT2ANLRP3
Hydrochloric Acid SCHEMBL2238154 0.81 KMT2A (0.47) RXFP1MEN1KMT2ANLRP3
SCHEMBL11973371 0.81 KMT2A (0.47) RXFP1MEN1KMT2ANLRP3
Phenylglycine SCHEMBL30559595 0.77 CYP2D6 (0.56) CYP2D6MEN1KMT2ASLC6A2SLC6A4
Phenylglycine SCHEMBL159420 0.77 CYP2D6 (0.56) CYP2D6MEN1KMT2ASLC6A2SLC6A4
Phenylglycine SCHEMBL11576917 0.77 CYP2D6 (0.56) CYP2D6MEN1KMT2ASLC6A2SLC6A4
Phenylglycine SCHEMBL157180 0.77 CYP2D6 (0.56) CYP2D6MEN1KMT2ASLC6A2SLC6A4
Phenylglycine SCHEMBL31402004 0.77 CYP2D6 (0.56) CYP2D6MEN1KMT2ASLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6235707-B1 Anticoagulant peptidyl-arginine aldehyde derivatives GYOGYSZERKUTATO INTEZET KFT. (HU) 2001-05-22 US disclosed