SCHEMBL7929339

SCHEMBL7929339

O=C(c1ccc(O)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.91

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.91
RAB9A P51151 3/20 0.91
LMNA P02545 2/20 0.91
MEN1 O00255 2/20 0.91
KMT2A Q03164 2/20 0.91
ESR1 P03372 1/20 0.68
ESR2 Q92731 1/20 0.68
PKM P14618 1/20 0.68
HPGD P15428 1/20 0.68
HTT P42858 1/20 0.68
MMP3 P08254 1/20 0.68
BCL2L1 Q07817 1/20 0.68
SRD5A2 P31213 1/20 0.64
DEGS1 O15121 1/20 0.61
CDC25B P30305 1/20 0.59
ATM Q13315 1/20 0.59
MAPK1 P28482 2/20 0.58
POLB P06746 1/20 0.58
CES2 O00748 1/20 0.58
NPC1 O15118 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7108563 0.98 RAB9A (0.96) MAPTRAB9ALMNAMEN1KMT2A
SCHEMBL17536704 0.98 RAB9A (0.96) MAPTRAB9ALMNAMEN1KMT2A
Biphenyl SCHEMBL7692075 0.98 RAB9A (0.87) MAPTRAB9ALMNAMEN1KMT2A
SCHEMBL2214895 0.95 RAB9A (1.00) MAPTRAB9ALMNAMEN1KMT2A
Benzophenone SCHEMBL5719480 0.93 RAB9A (0.95) MAPTRAB9ALMNAMEN1KMT2A
Methyl Alcohol SCHEMBL27534896 0.91 RAB9A (0.92) MAPTRAB9ALMNAMEN1KMT2A
SCHEMBL6420024 0.91 ESR1 (0.83) MAPTRAB9ALMNAMEN1KMT2A
SCHEMBL4671519 0.91 ESR1 (0.83) MAPTRAB9ALMNAMEN1KMT2A
SCHEMBL3470674 0.91 ESR1 (0.83) MAPTRAB9ALMNAMEN1KMT2A
SCHEMBL10535107 0.91 ESR1 (0.83) MAPTRAB9ALMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0194062-A3 POLYARYLETHER IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-11-20 EP claimed
EP-2935397-A1 INTERFACIAL PROCESSES FOR PREPARING PHOTOACTIVE ADDITIVES SABIC Global Technologies B.V. (NL) 2015-10-28 EP disclosed
US-20150259472-A1 INTERFACIAL PROCESSES FOR PREPARING PHOTOACTIVE ADDITIVES SABIC GLOBAL TECHNOLOGIES B.V. 2015-09-17 US disclosed
US-9045590-B2 Interfacial processes for preparing photoactive additives SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-06-02 US disclosed
US-20140179891-A1 INTERFACIAL PROCESSES FOR PREPARING PHOTOACTIVE ADDITIVES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-26 US disclosed
WO-2014100635-A1 INTERFACIAL PROCESSES FOR PREPARING PHOTOACTIVE ADDITIVES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-26 WO disclosed
EP-2373721-B1 ACETYLENIC AROMATIC POLYETHERKETONE NEXAM CHEMICAL AB (SE) 2014-06-25 EP disclosed
US-20120213978-A1 INK COMPOSITION, IMAGE FORMING METHOD, AND PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2012-08-23 US disclosed
US-20120213978-A1 INK COMPOSITION, IMAGE FORMING METHOD, AND PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2012-08-23 US disclosed
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed