SCHEMBL7929795

SCHEMBL7929795

CCCCCCCCOc1c(Nc2c(C)cccc2OC)c(Nc2c(C)cccc2OC)c(F)c2c1C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.39
PIM1 P11309 1/20 0.39
ELANE P08246 2/20 0.38
CNR1 P21554 3/20 0.37
CNR2 P34972 3/20 0.37
ALOX5 P09917 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7928407 0.96 EGFR (0.40) EGFRPIM1ELANE
SCHEMBL7933317 0.93 CNR1 (0.36) ELANECNR1CNR2
SCHEMBL7928353 0.92 ELANE (0.35) ELANECNR1CNR2
SCHEMBL7930916 0.89 ELANE (0.36) EGFRPIM1ELANE
SCHEMBL7929756 0.88 MAPK14 (0.35) ELANECNR1CNR2
SCHEMBL7929873 0.85 ELANE (0.38) EGFRPIM1ELANECNR1CNR2
SCHEMBL7933215 0.85 FAAH (0.38) ELANECNR1CNR2ALOX5
SCHEMBL7928349 0.85 EGFR (0.52) EGFRPIM1ELANE
SCHEMBL7929802 0.84 TSHR (0.38)
SCHEMBL7930360 0.84 ELANE (0.37) ELANECNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed