SCHEMBL7929902

SCHEMBL7929902

CCCCc1cccc(CCCC)c1Nc1c(F)c(F)c2c(c1F)C(=O)c1c(O)ccc(O)c1C2=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 7/20 0.46
CTSG P08311 5/20 0.46
TYR P14679 2/20 0.39
SLC37A4 O43826 1/20 0.37
BID P55957 4/20 0.36
MCL1 Q07820 4/20 0.36
BCL2L1 Q07817 3/20 0.36
BAK1 Q16611 3/20 0.36
KAT8 Q9H7Z6 2/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
EP300 Q09472 1/20 0.36
KAT2A Q92830 1/20 0.36
KAT2B Q92831 1/20 0.36
KAT5 Q92993 1/20 0.36
SAE1 Q9UBE0 1/20 0.36
MEN1 O00255 1/20 0.35
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933042 0.95 ELANE (0.48) ELANECTSGTYRSLC37A4BID
SCHEMBL7921158 0.88 CLCN2 (0.38) ELANECTSGMEN1TP53CYP3A4
SCHEMBL7928247 0.85 ELANE (0.41) ELANECTSGTYRSLC37A4BID
SCHEMBL7930697 0.84 TYR (0.47) ELANECTSGTYRSLC37A4MEN1
SCHEMBL7929731 0.84 ELANE (0.43) ELANECTSGMEN1TP53CYP3A4
SCHEMBL7929945 0.83 CLCN2 (0.40) ELANECTSGMEN1TP53CYP3A4
SCHEMBL7928267 0.81 ELANE (0.37) ELANECTSGMEN1MAPTKMT2A
SCHEMBL7927329 0.79 CLCN2 (0.38) ELANECTSGMEN1TP53CYP3A4
SCHEMBL7930686 0.79 ELANE (0.38) ELANECTSGSLC37A4MEN1MAPT
SCHEMBL7927144 0.78 ELANE (0.35) ELANECTSGMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed