Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 9/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18472043 | 0.81 | BRD4 (0.49) | BRD4MEN1KMT2A | |
| SCHEMBL17294389 | 0.81 | BRD4 (0.49) | BRD4MEN1KMT2A | |
| SCHEMBL21026694 | 0.81 | BRD4 (0.49) | BRD4MEN1KMT2A | |
| SCHEMBL688823 | 0.81 | BRD4 (0.49) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14856811 | 0.81 | BRD4 (0.49) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL793587 | 0.81 | MEN1 (0.46) | BRD4SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL20665982 | 0.81 | BRD4 (0.45) | BRD4CYP1A2PDE4APDE4BPDE4C | |
| SCHEMBL18014917 | 0.80 | BRD4 (0.49) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21872654 | 0.80 | BRD4 (0.47) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4464249 | 0.77 | BRD4 (0.45) | BRD4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616438-A1 | USE OF N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS AS SOLVENTS | Clariant Finance (BV) Limited (VG) | 2013-07-24 | — | — | EP | disclosed |
| EP-2615911-A1 | PESTICIDE PREPARATIONS CONTAINING N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS | Clariant Finance (BVI) Limited (VG) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012034689-A1 | PESTICIDE PREPARATIONS CONTAINING N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS | CLARIANT INTERNATIONAL LTD (CH) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012034688-A1 | USE OF N-SUBSTITUTED 2-PYRROLIDONE-4-CARBONIC ACID ESTERS AS SOLVENTS | CLARIANT INTERNATIONAL LTD (CH) | 2012-03-22 | — | — | WO | disclosed |